Improving Memory in Alzheimer's Disease with Noninvasive Brain Stimulation

This study is looking into whether a noninvasive brain stimulation technique, called high definition transcranial electrical current stimulation, can help improve memory in people with Alzheimer's disease. This treatment involves applying a low-intensity electrical current to the scalp to gently change how brain cells communicate. The researchers believe that memory problems in Alzheimer's may come from brain networks not working together efficiently, and this stimulation might help re-synchronize them. You may be able to join if you are 50 to 100 years old, have mild Alzheimer's dementia, and meet specific memory test scores. The study will measure memory performance during both active stimulation and a sham (inactive) stimulation, with results reported one year later. The current status of this study is unclear, and it aims to enroll 204 participants.

Study design
This is an interventional study with a planned enrollment of 204 participants. It compares active brain stimulation to sham stimulation.
What's involved
Participants will undergo low-intensity, high-definition, transcranial electrical current stimulation while performing computer-based tasks that test memory and cognitive function.
Compensation
Not stated in the trial record.
Follow-up
Memory performance data is collected during brain stimulation and reported one year later.

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NCT06094192

Improving Memory in Alzheimer's Disease With Noninvasive Brain Stimulation

Recruiting
NAAges 50+InterventionalBasic science
Boston University Charles River Campus
~204 participants
Updated 2025-09-19 on ClinicalTrials.gov
What's tested:High definition transcranial electrical current stimulation

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Memory performance (active stimulation condition)
Measured over Time Frame: Memory performance data is collected during active brain stimulation and reported 1 year later
+1 more outcome measured
Alzheimer Disease
1 sites across 1 states
Massachusetts1

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  • Memory performance (active stimulation condition)Time Frame: Memory performance data is collected during active brain stimulation and reported 1 year later

    The accuracy of task performance on memory test

  • Memory performance (sham stimulation condition)Time Frame: Memory performance data is collected during sham brain stimulation and reported 1 year later

    The accuracy of task performance on memory test