This study aims to understand how blood flow in your fat tissue (adipose tissue) changes as you age. Researchers want to see if there are differences in how blood flows to fat tissue between younger and older healthy adults, both normally and after drinking a sugary drink (75 gm oral glucose load). The study is looking for 24 healthy adults, aged 18-35 or 65-80, with a healthy weight (BMI between 20-25 kg/m2). You cannot have certain health conditions like diabetes or high blood pressure, or be taking medications that affect fat tissue. The main goal is to measure fat tissue blood flow before and after the sugary drink to see if it's different between age groups.

Study design

This is an interventional study, meaning participants will receive a specific intervention (the sugary drink). It plans to enroll 24 participants.

What's involved

You will have one visit where you'll give consent, have a body scan (DEXA), blood tests, an exercise test, and a pregnancy test if applicable. You'll then have blood flow measurements using a special technique (xenon washout), two small fat tissue biopsies from your abdomen, and drink a sugary drink.

Compensation

Not stated in the trial record.

Follow-up

Blood flow measurements are taken at baseline (before the sugary drink) and immediately after consuming the 75 gm oral glucose load.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.