Breast Cancer Resiliency Through Exercise Program (B-REP)

This study, called the Breast Cancer Resiliency Through Exercise Program (B-REP), is looking at how well a guided exercise program works for Black or African American or Afro-Latina/e women who have had breast cancer. You would either join a 12-week guided exercise program right away, or be on a waiting list for 24 weeks before being offered the same program. The researchers want to see if the exercise program is practical and if people stick with it. To join, you need to be a woman aged 18 or older, identify as Black or African American or Afro-Latina/e, have a confirmed diagnosis of breast cancer (Stage I to IIIA), and have finished your main treatments (surgery, chemotherapy, and radiation) within the last five years. The study is currently unclear on its recruitment status.

Study design
This study is a randomized controlled trial with two groups and plans to include 75 participants. One group receives the exercise program, and the other is a waitlist control.
What's involved
Participants will either take part in a 12-week guided exercise program or be on a waiting list for 24 weeks before starting the program. Assessments will occur at the beginning, after 12 weeks, and at 24 weeks.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to 24 weeks after the start of the intervention.

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NCT06100263

Breast Cancer Resiliency Through Exercise Program (B-REP)

Recruiting
NAAges 18+InterventionalSupportive care
University of Michigan Rogel Cancer Center
~75 participants
Updated 2026-02-10 on ClinicalTrials.gov
What's tested:Individualized exercise programControl Arm

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Feasibility of the exercise program (Retention)
Measured over up to 24 weeks after start of intervention
+6 more outcomes measured
Breast Cancer Female
1 sites across 1 states
Michigan1
  • Angela Fong, PhD · PRINCIPAL_INVESTIGATOR · University of Michigan Rogel Cancer Center

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Eligibility criteria

Inclusion

self-identify as Black or African American or Afro-Latina/e;
are ≥18 years old;
have a confirmed diagnosis of breast cancer, Stage I to IIIA;
have completed primary active treatment (i.e., surgery, chemotherapy, and radiation) within 5 years prior to study start where concomitant hormonal therapy is acceptable;
are not meeting current cancer-specific resistance exercise guidelines of ≥ 2 times per week; and
are able to speak and understand English.

Exclusion

metastatic disease;
medical reason that precludes them from increasing current exercise levels;
planned elective surgery during study period;
pregnant or plans to become pregnant during the study period;
plans to move out of United States during the study period; (the rationale for this exclusion is that it will be difficult to conduct the in-person assessments if a participant leaves the United States);
current enrollment in another exercise trial; and/or
inability to pass exercise pre-screening or receive physician consent to increase current physical activity levels.
  • Feasibility of the exercise program (Retention)up to 24 weeks after start of intervention

    Percent of patients that complete the intervention

  • Feasibility of the exercise program (Adherence)12 weeks after start of intervention

    Percent of patients that complete the exercise sessions

  • Feasibility of the exercise program (fidelity)12 weeks after start of intervention

    Upon completion of the trial, a random sample of 10 recorded sessions will be analyzed for fidelity. Research staff who did not conduct the intervention will use a "fidelity checklist" of specific exercises and intervention characteristics (e.g., allowing time for questions, cueing for proper posture and form, etc.) required for each exercise session..

  • Satisfaction of programup to 24 weeks after start of intervention

    14-item scale measuring ease of use, convenience, engagement, enjoyment, and privacy elements of the intervention.

  • Affective attitudeup to 24 weeks after start of intervention

    36-item scale assessing views, attitude, and experiences in exercise87

  • Perceived burdenup to 24 weeks after start of intervention

    Single item, "Now that you've completed this part of the study, how burdensome or difficult did you find the experience. Select the response that best represents your experience." (1= Very burdensome to 5= Not too burdensome.)

  • Outcome expectationup to 24 weeks after start of intervention

    15-item scale assessing physical, social, and self-evaluative outcomes of exercise