EBUS-TBNA vs. Cryobiopsy for Lung Cancer Tissue Analysis
This study is comparing two ways to collect tissue samples for lung cancer: Endobronchial ultrasound with transbronchial needle aspiration (EBUS-TBNA) and Transbronchial Mediastinal Cryobiopsy. The goal is to see which method is better at getting enough tissue for next-generation sequencing (NGS) tests, which help doctors understand your cancer better. You might be able to join if you have a suspected lung cancer lesion that can be biopsied and if initial tests show cancer cells. The study is looking for 250 participants and is currently unclear on its recruitment status. Success for this study means finding a method that provides enough tissue for these important genetic tests.
- Study design
- This is an interventional study comparing two biopsy procedures. It plans to enroll 250 participants.
- What's involved
- You would undergo a bronchoscopy procedure. During this procedure, you would be randomly assigned to either continue with an EBUS-TBNA needle or switch to a cryoprobe for tissue sampling.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary outcome of sufficient tissue for testing will be measured up to 12 months after the procedure.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
EBUS-TBNA vs Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Fabien Maldonado, MD · PRINCIPAL_INVESTIGATOR · Vanderbilt University/Ingram Cancer Center
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Proportion of samples sufficient for next-generation sequencing testingUp to 12 months
Comparison of samples between arms that meet sufficiency criteria for NGS