Exercise Regimens to Improve Muscle Mass After Breast Cancer Treatment

This study is looking at two different exercise programs to help women who have been treated for breast cancer increase their muscle mass. You could be eligible if you are a woman between 20 and 89 years old, have been diagnosed with breast cancer (ductal carcinoma in situ or invasive carcinoma), and have completed treatments like surgery, radiation, chemotherapy, immunotherapy, or hormonal therapy. However, you cannot be actively receiving chemotherapy to join. The study aims to see how much muscle and fat mass changes during and after an 8-week exercise program. The study is currently unclear on its recruitment status.

Study design
This interventional study plans to enroll 30 participants to compare two exercise regimens: one based on ACSM Guidelines and another using 6-12-25 repetitions per set.
What's involved
You would undergo a fitness evaluation, then participate in small group training sessions about 3 times per week for 12 weeks (3 months).
Compensation
Not stated in the trial record.
Follow-up
Muscle and fat mass will be measured during and after the 8-week exercise program.

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NCT06115486

EXERT-BCH Exercise Regimen to Improve Muscle Mass After Treatment of Breast Cancer

Recruiting
NAAges 20–89Interventional
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
~30 participants
Updated 2026-02-04 on ClinicalTrials.gov
What's tested:Control Arm ACSM GuidelinesExperimental Arm 6-12-25 repetitions per set

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Determine changes in muscle and fat mass during and after each exercise regimen
Measured over The exercise program will last for 8 weeks and continuously monitored by the PI and clinical team.
Breast Cancer
Breast Carcinoma in Situ
Breast Cancer Female
1 sites across 1 states
Pennsylvania1
  • Colin Champ, MD, CSCS · PRINCIPAL_INVESTIGATOR · Radiation Oncologist

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Eligibility criteria

Inclusion

Women with a biopsy proven diagnosis of ductal carcinoma in situ or invasive carcinoma of the breast
Women must have undergone treatment for breast cancer, including one or more of the following: surgery, radiation therapy, chemotherapy, immunotherapy, or hormonal therapy. Women undergoing active chemotherapy are not allowed on study. Immunotherapy or targeted agent usage is allowed.

Exclusion

Any current treatment with cytotoxic chemotherapy for breast cancer
Inability to safely engage in group sessions of resistance training as deemed by study PI
Severe arthritic, joint, cardiovascular, or musculoskeletal condition deemed by PI to be unsafe to engage in resistance training
  • Determine changes in muscle and fat mass during and after each exercise regimenThe exercise program will last for 8 weeks and continuously monitored by the PI and clinical team.

    The experimental group will follow a 6-12-25 program geared at optimizing hypertrophy and metabolism via high volume and increased time under tension.