Reducing Metabolic Dysregulation in Dyads

This 6-month study is looking for adults (ages 9-55) who are obese and have had at least one polyp found during a colonoscopy screening. You would also need to identify a partner (at least 9 years old and overweight) who lives with you. The study is testing an intervention called IMAGINE HEALTHY, which is an anti-inflammatory nutrition program. This program includes cooking classes, physical activity, and stress reduction. Researchers want to see if this program can help reduce chronic inflammation and reverse metabolic problems in people at risk for colorectal cancer. The study is currently unclear on its recruitment status and plans to enroll 180 participants.

Study design
This is a 6-month randomized controlled trial. It aims to enroll 180 participants.
What's involved
You would participate in an anti-inflammatory nutrition program including cooking classes, physical activity, and stress reduction. Blood and stool samples will be collected at the beginning, 3 months, and 6 months.
Compensation
Not stated in the trial record.
Follow-up
Your blood and stool will be measured at 3 months and 6 months after starting the study.

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NCT06117241

Reducing Metabolic Dysregulation in Dyads

Recruiting
NAAges 9–55InterventionalPrevention
University of South Carolina
~180 participants
Updated 2026-01-29 on ClinicalTrials.gov
What's tested:IMAGINE HEALTHY

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blood
Measured over Baseline, 3-month, 6-month
+1 more outcome measured
Colorectal Cancer
Inflammation
Nutrition Related Cancer
1 sites across 1 states
South Carolina1

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  • BloodBaseline, 3-month, 6-month

    Tumor Necrosis Factor alpha (TNFα), Interleukin 6 (IL-6), and C-Reactive Protein (CRP)

  • StoolBaseline, 3-month, 6-month

    Determine race-specific microbiome signatures associated with anti-inflammatory dietary input and reversal of metabolic dysfunction