Observational Study of Brain-Gut Axis and Gut Microbiome in Brain Lesions
This study is looking at how the tiny living organisms in your gut (your gut microbiome) might affect brain tumors. Researchers want to understand if there's a connection between your gut health and how brain tumors develop, grow, and respond to treatments like chemotherapy, radiation, or immunotherapy. You could join if you are 18 or older and are having surgery for a central nervous system tumor. The main goal is to collect samples and information to build a resource (biorepository) that will help future research. This collection is expected to take about one year, or until enough samples are gathered based on treatment schedules. The study is currently observational, meaning it involves collecting information and samples without giving any new treatments.
- Study design
- This is an observational study planning to enroll 100 participants. It is not testing a specific drug or intervention.
- What's involved
- You would provide blood, tissue, saliva, urine, and stool samples, and complete questionnaires.
- Compensation
- Not stated in the trial record.
- Follow-up
- The primary goal of establishing the biorepository is measured at approximately 1 year, or until samples have been collected based on scheduled treatment.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Alfredo Quinones-Hinojosa, M.D. · PRINCIPAL_INVESTIGATOR · Mayo Clinic
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Establish the Mayo Clinic Florida Tumor-Gut Axis BiorepositoryApproximately 1 year, or until samples have been collected based on scheduled treatment.
Biological samples such as stool, urine, blood, saliva, and/or tissue will be collected for storage in the Tumor-Gut Axis Biorepository. Samples may be collected at any of the following time periods during study participation: before/after steroid therapy, before/after surgical intervention, before/after radiation therapy, and before/after chemotherapy.