iTBS to Enhance Social Cognition in People With Psychosis
This study is looking at whether a treatment called iTBS (intermittent Theta Burst Stimulation) can improve social thinking skills in people with certain psychotic disorders, including schizophrenia and schizoaffective disorder. iTBS uses magnetic pulses to stimulate a specific area of the brain (DMPFC). You could be eligible if you are 18-39 years old, have one of these diagnoses, and have been on a stable dose of antipsychotic medication for a certain period. The study will compare iTBS to a sham (inactive) treatment to see if it improves social cognitive performance. The goal is to see if iTBS helps people better understand and respond to social cues.
- Study design
- This is a double-blind, randomized clinical trial aiming to enroll 100 participants. This means neither you nor the study team will know if you are receiving the active iTBS or the sham treatment.
- What's involved
- Each participant will receive iTBS (active or sham) five days per week for four consecutive weeks. Your social cognitive performance will be measured from the start of the study up to 4 weeks later.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your social cognitive performance will be measured from the start of the study up to 4 weeks after treatment begins.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
iTBS to Enhance Social Cognition in People With Psychosis
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Change in social cognitive performanceFrom baseline to 4 weeks
Measured using the emotion recognition (ER-40) task
- Change in social cognitive performanceFrom baseline to 4 weeks
Measured using the reading the mind in the eyes (RMET) task
- Change in social cognitive performanceFrom baseline to 4 weeks
Measured using the test of the awareness of social inference-revised (TASIT-R)