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Biobank of Nasal Epithelium Samples From Healthy Volunteers

This study is collecting cell samples from the inside of healthy people's noses to create a biobank (a collection of biological samples). These samples will be used by researchers to learn more about how respiratory viruses, like those that cause colds or the flu, infect the nose, spread to the lungs, and pass between people. There is no specific intervention or drug being tested. You can join if you are a healthy adult, aged 18 to 99 years old, and are willing to have your samples stored for future research. The goal is to collect samples from about 120 healthy volunteers to help understand and fight emerging respiratory viruses.

Study design
This is an observational study aiming to collect samples from approximately 120 healthy volunteers.
What's involved
You would provide nasal epithelium brushes (cell samples from your nose). These samples will be stored for future research.
Compensation
Not stated in the trial record.
Follow-up
Your biological samples and data will be stored for future research for up to 10 years.

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NCT06120244

Establishment of Biobank of Nasal Epithelium Samples From Healthy Volunteers

Recruiting
Not specifiedAges 18–99Observational
National Institute of Allergy and Infectious Diseases (NIAID)
~120 participants
Updated 2026-08-12 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To obtain nasal epithelium brushes from healthy volunteers for 1) establishment of upper respiratory tract organoids, 2) assay validation, and 3) use for research into the pathogenesis of emerging respiratory viruses.
Measured over 10 years

Conditions

Healthy

Explore related trials

Healthy

Where it's being run

1 sites across 1 states
Montana1

Study leadership

  • Emmie de Wit, Ph.D. · PRINCIPAL_INVESTIGATOR · National Institute of Allergy and Infectious Diseases (NIAID)

Who to contact

Emmie de Wit, Ph.D.
[email protected]
(406) 375-7490
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Aged \>=18 years.
Able to provide informed consent.
Willing to allow biological samples and data to be stored for future research.

Exclusion

History of respiratory symptoms including but not limited to runny nose, coughing, congestion, and/or fever within the past 14 days.
NIH and laboratory staff with direct involvement in the operation or maintenance of the repository are excluded from participation.
An individual who has any condition that, in the judgment of the investigator, may put them at undue risk or make them unsuitable for participation in the study will be excluded.

What this trial measures

  • To obtain nasal epithelium brushes from healthy volunteers for 1) establishment of upper respiratory tract organoids, 2) assay validation, and 3) use for research into the pathogenesis of emerging respiratory viruses.10 years

    To obtain nasal epithelium brushes from healthy volunteers for 1) establishment of upper respiratory tract organoids, 2) assay validation, and 3) use for research into the pathogenesis of emerging respiratory viruses.