Cannabidiol for Fear Reduction in Social Anxiety Disorder

This study is looking at whether cannabidiol (CBD) can help reduce fear in people with social anxiety disorder (SAD). You would be randomly assigned to receive either oral cannabidiol capsules or a placebo (an inactive capsule). Researchers will then see if cannabidiol helps you reduce your fear response during a specific task where you learn to overcome fear. Success in this study means participants taking CBD show lower skin conductance (a measure of anxiety) and report less distress during this task. The study plans to enroll 20 participants, but its current status is unclear.

Study design
This is a randomized, double-blind study, meaning participants are randomly assigned to a group and neither you nor the researchers will know if you're receiving cannabidiol or placebo. It plans to include 20 participants.
What's involved
You would participate in a single 2.5-hour session. This includes a fear conditioning task where you receive mild electrical stimulation paired with angry faces, then take the study medication, and finally undergo a fear extinction phase.
Compensation
Not stated in the trial record.
Follow-up
Your skin conductance and distress ratings will be measured during a single 2.5-hour session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06123702

Cannabidiol Effects on Fear Extinction in Social Phobia

UNKNOWN
EARLY_PHASE1Ages 18+InterventionalBasic science
Hartford Hospital
~20 participants
Updated 2024-04-19 on ClinicalTrials.gov
What's tested:Fear extinctionCannabidiol Cap/TabPlacebo

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Skin conductance
Measured over Single session (2.5 hours)
+1 more outcome measured
Social Anxiety Disorder

NCT06123702

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Anxiety Disorders Center, Institute of Living

    Hartford, Connecticutno site contact published

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • David Tolin, Ph.D. · PRINCIPAL_INVESTIGATOR · Hartford Hospital

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  • Skin conductanceSingle session (2.5 hours)

    Galvanic skin responses to conditioned stimuli

  • Distress ratingsSingle session (2.5 hours)

    Subjective units of discomfort (0-100, 100 = maximum distress)