Exercise and Emotional Learning in PTSD
This study is looking at how exercise might help people with Posttraumatic Stress Disorder (PTSD) learn and remember things that are helpful for their recovery. Researchers want to see if moderate intensity exercise, like cycling at a steady pace, after thinking about traumatic memories, can improve how the brain processes fear. You might be able to join if you are an adult between 18 and 64 years old with PTSD from interpersonal violence. The study is comparing moderate intensity exercise to low intensity exercise (slower cycling). Success will be measured by changes in your emotional ratings, heart rate, and brain activity related to fear after 24 and 48 hours. The current status of this study is unclear.
- Study design
- This interventional study plans to enroll 100 participants. It compares two groups: one doing moderate intensity exercise and another doing low intensity exercise.
- What's involved
- You would complete an initial visit, followed by two experimental sessions. These sessions involve an MRI scan, thinking about traumatic memories, and then 30-40 minutes of cycling.
- Compensation
- Not stated in the trial record.
- Follow-up
- Your emotional ratings and heart rate will be measured 24 hours after an experimental session, and brain activity will be measured 48 hours after.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Exercise and Emotional Learning in Posttraumatic Stress Disorder
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Thomas G Adams, Jr., PhD · PRINCIPAL_INVESTIGATOR · University of Kentucky
- Christal Badour, PhD · PRINCIPAL_INVESTIGATOR · University of Kentucky
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Change in participant subjective emotional ratings24 hours
Participant anxiety will be measured at baseline and after each imagery trial using a 10-point Likert-type scale with higher scores indicative of more subjective anxiety.
- Change in Heart Rate24 hours
Participant heart rate will be measured at baseline and after each imagery trial using a Biopac MP160 system
- Change in Fear Circuit Blood Oxygen Level-Dependent (BOLD) Response48 hours
Blood Oxygen Level-Dependent (BOLD) imaging will be measured during each imagery trial