Brain and Balance Study Across Adulthood
This study is looking at how brain blood flow and brain activity are connected to balance as people age. Researchers want to understand this relationship better by studying 102 healthy adults across different age groups: young (21-30), middle-aged (40-55), and older (65-95). You would be considered if you are neurotypical (meaning your brain development and function are typical) and cognitively normal (meaning you have no significant memory or thinking problems). The study will involve a single session of aerobic exercise to see how your brain's blood flow changes. They will also measure your balance after a small push and look at brain activity using EEG (electroencephalography) to understand how different brain areas work together.
- Study design
- This is a single-arm study, meaning all participants receive the same intervention, and it involves 102 participants. It is not blinded, so both you and the researchers will know about the exercise intervention.
- What's involved
- You would participate in two visits. During these visits, you would engage in a single session of aerobic exercise on a recumbent stepper machine.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for the main outcomes are taken at 1 week.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Jacqueline Palmer · PRINCIPAL_INVESTIGATOR · University of Minnesota
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- cerebral blood flow velocity assessed using transcranial Doppler ultrasound1 week
Includes recordings from transcranial Doppler ultrasound of cerebral blood flow (CBF) velocity performed at the first session during rest, sit-to-stand, transfer, and single bout of aerobic exercise.
- Kinetic center of pressure rate of rise post-balance perturbation, assessed biomechanically.1 week
Recordings from 64-channels of EEG electrodes, kinetic, and kinematic biomechanical data during standing balance reactions will be collected.
- Prefrontal-M1 coherence an S1-M1 coherence post-balance perturbation, assessed using EEG1 week
Recordings from 64-channels of EEG electrodes, kinetic, and kinematic biomechanical data during standing balance reactions will be collected.