Acute Equol Supplementation and Vascular Function in Women With and Without CKD

This study is looking at how a supplement called S-equol might affect blood vessel health in women. Researchers want to see if S-equol can improve how well blood vessels work, especially in women with chronic kidney disease (CKD) and those without it. You might be able to join if you are a woman between 50 and 69 years old and are postmenopausal. The study will compare S-equol to a placebo (an inactive substance) to see if S-equol helps improve a measure of blood vessel function called Brachial Artery Flow-Mediated Dilation. This measurement will be taken at the beginning and then 1, 2, and 3 hours after taking the supplement.

Study design
This is an interventional study planning to enroll 38 women. It compares the effects of S-equol to a placebo.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Blood vessel function will be measured at baseline, then 1, 2, and 3 hours after taking the supplement.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06128278

Acute Equol Supplementation and Vascular Function in Women With and Without CKD

Recruiting
PHASE2Ages 50–69InterventionalTreatment
University of Colorado, Denver
~38 participants
Updated 2025-09-30 on ClinicalTrials.gov
What's tested:S-equolPlacebo

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in Brachial Artery Flow-Mediated Dilation
Measured over Baseline; 1-hour, 2-hours, and 3-hours post ingestion
Chronic Kidney Diseases
Vascular Function
Women

NCT06128278

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Colorado Anschutz Medical Campus

    Aurora, Coloradostudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

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  • Change in Brachial Artery Flow-Mediated DilationBaseline; 1-hour, 2-hours, and 3-hours post ingestion

    Flow-mediated dilation of the brachial artery will be performed using ultrasonography and analyzed with a commercially available software package as percent change in diameter from baseline following reactive hyperemia.