Hyperbaric Oxygen Therapy for Optic Neuropathies

This study is looking into whether Hyperbaric Oxygen Therapy (breathing pure oxygen in a special chamber) can help protect the nerves in your eyes if you have optic neuropathy (damage to the optic nerve) or glaucoma. Researchers want to see if this treatment can improve your vision. You might be able to join if you are at least 18 years old and can follow the study's instructions. The study will compare Hyperbaric Oxygen to a sham treatment (breathing regular air at normal pressure). Success will be measured by changes in your visual field (how well you see in different directions) over six months. The current status of this study is unclear, and it plans to enroll 60 participants.

Study design: This interventional study plans to enroll 60 participants. It compares Hyperbaric Oxygen to a sham treatment.
What's involved: Not specified in the trial record.
Compensation: Not stated in the trial record.
Follow-up: Participants will be followed for 6 months after treatment to measure changes in their visual field.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

Hyperbaric Oxygen Therapy for Optic Neuropathies

Recruiting

NAAges 18+InterventionalTreatment

Stanford University

~60 participants

Updated 2025-05-25 on ClinicalTrials.gov

What's tested:Hyperbaric OxygenSham Hyperbaric Oxygen

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Change in Visual Field- Mean Deviation

Measured over Baseline through 6 months

+1 more outcome measured

Conditions

Optic Neuropathy

Glaucoma

Where it's being run

1 sites across 1 states

California1

Study leadership

Jeffrey L Goldberg, MD PhD · STUDY_CHAIR · Stanford University

Who to contact

Zac Wennberg Smith

[email protected]

6504975942

Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Patients must meet all of the following criteria to join the study (all eligibility criteria must be met at the screening and baseline visits unless otherwise noted):

Participant must be at least 18.

Participant must has the ability to comply with the requirements of the study and complete the schedule of events (SOE).

Participant's with clinical evidence of optic neuropathy.

Participant must understand and sign the informed consent. If the participant's vision is impaired to the point where he/she cannot read the informed consent document, the document will be read to the participant in its entirety.

Exclusion

Participant is unable to comply with study procedures or follow-up visits.

Participant has evidence of corneal opacification or lack of optical clarity.

Participant is currently participating in or has within the last 3 months participated in any other clinical trial of a drug by ocular (if in the study eye) or systemic administration.

Participant is pregnant or lactating.

Participant has, in the opinion of the investigator, any physical or mental condition that would increase the risk of participation in the study or may interfere with the study procedures, evaluations and outcome assessments.

Children and comatose patients.

Participant abusing drugs or alcohol.

Prior treatment with hyperbaric oxygen within the last 6 months.

Participant with claustrophobia or that cannot decompress properly.

What this trial measures

Change in Visual Field- Mean DeviationBaseline through 6 months
Humphrey visual field testing with standard MD output
Change in Visual Field- Visual Field IndexBaseline through 6 months
Humphrey visual field testing with standard VFI output

Trialytics