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AvoCog: Avocado Intake and Brain Function in Older Adults

This study, called AvoCog, is looking at whether eating avocados every day can improve brain function in older adults. We are inviting 70 people between 65 and 85 years old who are in good general health and don't have dementia. Participants will either add avocados to their daily diet for 12 weeks or continue their usual eating habits. We will measure changes in brain activity using special scans (functional MRI), cognitive tests, and brain blood flow to see if avocados have a positive effect. We are currently unclear on the status of this study.

Study design
This interventional study plans to enroll 70 participants aged 65-85. Participants will be divided into groups, with one group consuming avocados daily.
What's involved
Participants will consume provided avocados daily for 12 weeks or maintain their normal diet. They will also undergo cognitive tests, MRI scans, blood tests, and complete questionnaires.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint is measured at 12 weeks, indicating the study duration for observing changes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06137339

AvoCog - the Effect of Daily Avocado Intake on Cognitive Function in Older Adults

UNKNOWN
NAAges 65–85InterventionalPrevention
University of Kansas Medical Center
~70 participants
Updated 2024-08-22 on ClinicalTrials.gov
What's tested:Avocado Group

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in brain activity
Measured over Baseline and 12 weeks

Conditions

Brain Aging

Explore related trials

Cognitive Dysfunction

NCT06137339

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Kansas Medical Center

    Kansas City, Kansasstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Who to contact

Emma Kelly, MS
[email protected]
913-588-7683
Email the study team

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Eligibility criteria

Inclusion

Males and females aged 65-85 years
Good general health with no concomitant disease
BMI 18.5 - 35 kg/m2
Mini Mental State Exam ≥26
Reports consuming ≤2 medium avocados per month
Reports consuming ≤3 servings of carotenoid-rich foods per week and ≤3 servings of fruits and vegetables per day
Skin carotenoid content \<400

Exclusion

Unwilling or unable to consume avocado
Latex allergy
Consistently taking lutein + zeaxanthin supplements
Skin carotenoid content ≥400
Central neurological disease such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, brain tumor, etc.
Serious medical risk: cancer requiring chemotherapy or radiation within the past 5 years, recent cardiac event (i.e. heart attack, etc.)
Diabetes mellitus or uncontrolled hypertension
Use of psychoactive or investigational medications
Consumption of ≥3 alcoholic drinks per day or substance abuse
Unable to undergo MRI

What this trial measures

  • Change in brain activityBaseline and 12 weeks

    MRI will be used to measure changes in brain activity during resting state, a working memory task, and executive function task.