NCT06139172

Web Intervention for Parents of Youth With Genetic Syndromes (WINGS)

Active, Not Recruiting
NAAges 2–12InterventionalTreatment
Rush University Medical Center
~92 participants
Updated 2026-07-13 on ClinicalTrials.gov
What's tested:Functional Behavioral Training (FBT)Positive Parenting Strategies-Treatment as Usual

At a glance

Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Clinical Global Impression
Measured over TO (Baseline), T2 (Month 2), T4 (Month 4), T6 (Month 6)
Telomeric 22Q13 Monosomy Syndrome
Tuberous Sclerosis
Hamartoma Syndrome, Multiple
Fragile X Syndrome
Angelman Syndrome
Rett Syndrome
Chromosome 15Q, Partial Deletion
Creatine Deficiency, X-linked
1 sites across 1 states
Illinois1

This trial hasn't published a contact. View it on ClinicalTrials.gov

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Eligibility criteria

Inclusion

Age(s) 2-12 years old at time of enrollment
Existing genetic syndrome based on clinical or genetic diagnosis and confirmed by medical records
Documented diagnosis of global developmental delay (GDD) or intellectual disability (ID)
estimated ID in all ranges
Disruptive behavior challenges determined to be clinically appropriate for remote, parent-implemented coaching based on clinician determination of acuity of problem behaviors
Caregiver who is able to consent in English.
Parent/caregiver available for weekly intervention sessions
Stable psychosocial and psychiatric treatments 3 months prior to baseline visit.

Exclusion

High levels of aggression that mitigate remote or outpatient treatment as defined by clinician judgement and/or ABC Irritability scores above 20 (i.e., higher level of care needed than provided by study procedures)
Medical or psychiatric instability that may limit study participation
Meaningful change in medication or psychosocial interventions 3 months prior to baseline visit
Limitations in technology access that may hinder participation in remote trial (e.g., declining support provided by study participation)
  • Clinical Global ImpressionTO (Baseline), T2 (Month 2), T4 (Month 4), T6 (Month 6)

    Overall functioning will be measured using the Clinical Global Impression for Severity (CGI-S) and Improvement (CGl-I). GCI-S will be recorded at Baseline with CGI-S and CGI-I collected at all determined visits. The CGI provides a rating of the child's global functioning, taking into account all available information (e.g., child's symptoms, behavior, functioning). The CGI-S and CGl-I will be completed by a blinded independent evaluator.