Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

This study is looking at how accurate pulse oximeters are. These devices measure the oxygen in your blood by shining light through your finger, without needing a blood sample. Researchers will compare pulse oximeter readings to a "gold standard" blood test while participants breathe air with lower oxygen levels (hypoxia). This helps ensure the devices give correct readings for people with different skin tones. You might be able to join if you are a healthy male or female between 18 and 50 years old. The main goal is to measure blood oxygen levels (SpO2) by August 1, 2025. The study status is currently unclear.

Study design
This is an observational study planning to enroll 10,000 healthy participants. It is not specified if it is randomized or blinded.
What's involved
Participants will breathe hypoxic air mixtures to create stable low oxygen levels. This involves having blood samples taken from an arterial line, potentially up to 35 samples, and having pulse oximeter probes placed on various body parts.
Compensation
Not stated in the trial record.
Follow-up
The primary endpoint for measuring blood oxygen (SpO2) is set for August 1, 2025. The duration of individual participant follow-up is not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06142019

Pulse Oximeter Accuracy in Healthy Humans During Hypoxia

Recruiting
Not specifiedAges 18–50Observational
University of California, San Francisco
~10,000 participants
Updated 2025-09-02 on ClinicalTrials.gov
What's tested:Controlled desaturation (hypoxemia)

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
SpO2
Measured over 08/01/2025
Hypoxia
Skin Pigmentation
1 sites across 1 states
California1
  • Philip E Bickler, MD, PhD · PRINCIPAL_INVESTIGATOR · University of California at San Francisco

Opens a ready-to-send draft in your own email app — review before sending.

  • SpO208/01/2025

    Reading on pulse oximeter device which is an estimate of the patient's blood oxygen level.