This study, called the RESBIOP-study, is looking at the best way to treat high-grade glioma (a type of brain tumor) in older patients or those who have limited physical function. Doctors are comparing two surgical approaches: maximal safe resection (removing as much of the tumor as possible) versus tumor biopsy (taking a small sample of the tumor). The goal is to see which approach leads to better overall survival, how well patients function, their neurological health, and quality of life. The study also wants to find out which method allows more patients to receive additional treatments like chemotherapy and radiation. You may be able to join if you are between 18 and 90 years old and have been diagnosed with a high-grade glioma.

Study design

This is an international, observational study involving many centers. It will include 564 participants who will receive either tumor resection or tumor biopsy.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Your overall survival will be measured for up to 5 years after surgery, and adjuvant treatment will be checked at 6 months postoperatively.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.