Nutrition for Asthmatics Study

This study is looking at how different diets might help people with asthma. Researchers want to see if a standard diet (DGA Diet), a standard diet with added medium chain triglycerides (MCT Diet), or a ketogenic diet (KETO Diet) can improve asthma control and lung function. You might be able to join if you are between 18 and 65 years old, have asthma diagnosed by a specialist, and your asthma is partly controlled or uncontrolled. The study will measure your asthma control at the beginning and after you try each diet. The current status of this study is unclear, and it plans to enroll 15 participants.

Study design
This is a pilot study with 15 adult participants. It uses a crossover design, meaning each participant will try all three diets.
What's involved
You will undergo screening, a lead-in period, and then follow three different 7-day diets. There will be a break of at least 7 days between each diet.
Compensation
Not stated in the trial record.
Follow-up
Your asthma control will be measured after 7 days on each diet.

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NCT06151405

Nutrition for Asthmatics

Recruiting
NAAges 18–65InterventionalTreatment
Pennington Biomedical Research Center
~15 participants
Updated 2024-09-19 on ClinicalTrials.gov
What's tested:DGA DietMCT DietKETO Diet

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Asthma Control
Measured over Baseline
+7 more outcomes measured
Asthma
1 sites across 1 states
Louisiana1
  • Jacob T Mey, PhD, RD · PRINCIPAL_INVESTIGATOR · Pennington Biomedical Research Center

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Eligibility criteria

Inclusion

Age: 18-65 years
BMI: 18.5 - 29.99 kg/m2
asthma diagnosed by medical specialist (confirmed in medical history)
partly controlled or uncontrolled asthma by Asthma Control Test score ≤22
owns a device compatible with ZEPHYRx platform
stable asthma medication use (no change in the past 2 months).

Exclusion

Diabetes or using diabetes medications that may lower blood glucose levels
point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl
current smoking or smoking history of greater than 10 pack-years
other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg
pregnant or nursing women
food preferences or allergies inconsistent with study diet capabilities
noncompliance with lead-in period requirements.
  • Asthma ControlBaseline

    Asthma Control Questionnaire score (Juniper; 1 week recall period) Score range: 0-6. Minimally important difference = 0.5.

  • Asthma ControlAfter 7 days on Diet#1

    Asthma Control Questionnaire score (Juniper; 1 week recall period) Score range: 0-6. Minimally important difference = 0.5.

  • Asthma ControlAfter 7 days on Diet#2

    Asthma Control Questionnaire score (Juniper; 1 week recall period) Score range: 0-6. Minimally important difference = 0.5.

  • Asthma ControlAfter 7 days on Diet#3

    Asthma Control Questionnaire score (Juniper; 1 week recall period) Score range: 0-6. Minimally important difference = 0.5.

  • Lung FunctionBaseline

    FEV1 (forced expiratory volume in 1 second; % of predicted)

  • Lung FunctionAfter 7 days on Diet#1

    FEV1 (forced expiratory volume in 1 second; % of predicted)

  • Lung FunctionAfter 7 days on Diet#2

    FEV1 (forced expiratory volume in 1 second; % of predicted)

  • Lung FunctionAfter 7 days on Diet#3

    FEV1 (forced expiratory volume in 1 second; % of predicted)