This study is looking at whether patients who have a nipple-sparing mastectomy (NSM) are willing to join a larger study comparing NSM with or without a procedure called neurotization. Neurotization is a surgical technique that uses a nerve graft to try and restore sensation to the nipple and areola (the darker skin around the nipple). Many patients who have NSM report less nipple sensation, and this study also wants to see if neurotization can improve quality of life and sexual function. This study is for women aged 18 or older who are planning to have an NSM for certain stages of breast cancer (Anatomic Stage 0, I, or IIA). The main goal is to see how many patients are willing to participate in a randomized study comparing these two approaches. About 20 patients are expected to enroll.

Study design

This is an interventional study that will randomly assign participants to either receive standard nipple-sparing mastectomy (NSM) or NSM with neurotization. It aims to enroll 20 women.

What's involved

Participants will undergo either a standard NSM or an NSM with a nerve graft. They will also complete questionnaires and have follow-up appointments.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for up to 2 years after their surgery, with appointments at 14 days, and at 6, 12, and 24 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.