Exercise for Metastatic Prostate Cancer

This study is looking at how a 12-week exercise program affects men with advanced prostate cancer that has spread (metastatic prostate adenocarcinoma). You could join if you are between 18 and 80 years old, male, and are currently taking hormone therapy (androgen deprivation therapy) alone or with other oral medications like abiraterone, enzalutamide, darolutamide, or apalutamide for at least three months. The main goal is to see if exercise can reduce the number of circulating tumor cells (CTCs) in your blood. The study aims to enroll 20 participants, but its current status is unclear.

Study design
This is a small, single-arm study, meaning all 20 participants will receive the exercise intervention. It is a pilot study to explore the effects of personalized exercise training.
What's involved
You would have initial screening, participate in a 12-week exercise program, and then have follow-up assessments 12 weeks after the exercise ends.
Compensation
Not stated in the trial record.
Follow-up
Your health records will be monitored for 365 days after the study completion to track your vital status.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06165302

Exercise in Prostate Cancer

Recruiting
NAAges 18–80Interventional
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
~20 participants
Updated 2025-10-20 on ClinicalTrials.gov
What's tested:Exercise Intervention

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of participants with negative CTC count
Measured over Baseline, 12 weeks
Prostate Cancer Metastatic
Prostate Cancer
1 sites across 1 states
Maryland1
  • Cathy Marshall, MD · PRINCIPAL_INVESTIGATOR · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

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  • Number of participants with negative CTC countBaseline, 12 weeks

    Number of participants with negative CTC count at 12 weeks compared to the baseline