Guided Meditation During Radiation Therapy for Brain Tumors

This study is looking at whether guided meditation can help reduce anxiety in people receiving radiation therapy for brain tumors. If you are 18 or older, have a brain tumor, and are scheduled for 25-33 radiation treatments, you might be able to join. Participants will either listen to a 10-15 minute audio-recorded guided meditation during each radiation session or receive standard care. The main goal is to see if guided meditation changes anxiety levels after 7 weeks compared to those who don't receive the meditation. The study aims to enroll 30 people, but its current recruitment status is unclear.

Study design
This study is an interventional study, meaning participants will receive a specific intervention. It plans to enroll 30 participants.
What's involved
Participants will be asked to participate in a 5-minute, audio-recorded mindfulness practice that will be played during the administration of each radiation therapy session.
Compensation
Not stated in the trial record.
Follow-up
Anxiety levels will be measured at 7 weeks after the start of the intervention.

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NCT06165653

Guided Meditation During Radiation Therapy for Brain Tumors

Recruiting
NAAges 18+InterventionalTreatment
University of Utah
~30 participants
Updated 2026-03-20 on ClinicalTrials.gov
What's tested:10 to 15-Minute, Audio-Recorded Guided Mediation Practice

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in acute anxiety, measured by score on individual item derived from GAD-2, in participants receiving mindfulness intervention during RT compared to standard of care control conditions.
Measured over 7 weeks
Brain Neoplasms
1 sites across 1 states
Utah1
  • Lindsay Burt, MD · PRINCIPAL_INVESTIGATOR · Huntsman Cancer Institute

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Eligibility criteria

Inclusion

Participant aged ≥ 18 years.
Radiologically confirmed tumor of the brain. Note: Participants may have tumor resected after diagnosis.
Eligible to undergo radiation treatment for brain tumor for 25-33 treatments.
Willing to participate in either the guided meditation or standard of care control arm, regardless of treatment assignment.
Karnofsky performance score ≥ 60 or ECOG performance score ≤ 2.
MoCA mini score ≥ 11
Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines.

Exclusion

Active suicidal ideation or active psychotic state in the opinion of the investigator.
An unstable illness that, in the opinion of the investigator, would interfere with study treatment.
Prior radiation therapy to the brain.
Inability to understand and/or speak the English language.
  • Change in acute anxiety, measured by score on individual item derived from GAD-2, in participants receiving mindfulness intervention during RT compared to standard of care control conditions.7 weeks

    To assess the acute anxiolytic effects of a brief mindfulness intervention during RT for brain tumor patients with mask anxiety. Acute anxiety during RT will be measured each RT visit with an individual item ("How nervous, anxious or on edge do you feel right now?" scored on a 0-10 scale) derived from the Generalized Anxiety Disorder 2-item (GAD-2) scale, "0" meaning "Not at All" and "10" meaning "Very Much") measured before and after RT. The change from before to after RT will be averaged over all RT visits.