Sleep Extension for Overweight and Obesity
This study is looking at how increasing the amount of time you sleep might affect certain fats in your blood called ceramides, and how your body uses sugar (insulin sensitivity). You could join if you are between 18 and 45 years old, are overweight or have obesity, and usually sleep less than 6.5 hours per night. The study will compare people who try to sleep 2 hours more each night with people who receive general health information. Researchers will measure your total plasma ceramides and insulin sensitivity right after the intervention to see if more sleep makes a difference. The study aims to enroll 70 participants.
- Study design
- This is a randomized controlled trial, meaning participants will be randomly assigned to either the sleep extension group or a control group. Researchers and participants will not know which group they are in until after the initial phase.
- What's involved
- You will have an initial screening for sleep disorders and about one week of at-home monitoring. After that, you will be in either the sleep extension or control group for 8 weeks, with regular contact with the study team. You will also have overnight lab visits to measure ceramides and insulin sensitivity.
- Compensation
- Not stated in the trial record.
- Follow-up
- Measurements for the primary outcomes (total plasma ceramides and insulin sensitivity) are taken immediately after the 8-week intervention period.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
At a glance
Conditions
Where it's being run
1 sites across 1 statesWho to contact
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What this trial measures
- Total Plasma CeramidesImmediately after the intervention
Total plasma ceramides will be measured by assessing plasma ceramides by targeted metabolomics.
- Insulin SensitivityImmediately after the intervention
Insulin sensitivity will be measured by the glucose infusion rate per kg body weight during the hyperinsulinemic-euglycemic clamp.