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iCardia4HF: Mobile Health for Heart Failure Self-Care

This study, called iCardia4HF, is looking at how mobile health tools can help people with heart failure (when your heart can't pump enough blood). It's testing two main approaches: "MyApps," which uses consumer mobile health apps and devices, and "Text4HF," which sends behavioral text messages about heart failure self-care. Some participants will receive both. You might be able to join if you are 18 or older, have Stage C Heart Failure, and have been hospitalized for heart failure in the last two years. The study wants to see if these tools can reduce the number of days you spend in the hospital due to heart problems or death, measured over 6 months. The recruitment status is currently unclear.

Study design
This is an interventional study with a planned enrollment of 360 participants. It is a randomized trial, meaning participants will be assigned to different groups by chance.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The main goal of the study is measured at 6 months, looking at days lost due to hospitalizations or death.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06205225

iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure

Recruiting
NAAges 18+InterventionalTreatment
University of Illinois at Chicago
~360 participants
Updated 2026-01-30 on ClinicalTrials.gov
What's tested:Text4HFMyAppsMyApps & Text4HFEnhanced Usual Care

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Percentage of days lost due to unplanned cardiovascular hospitalizations or death from any cause
Measured over 6 months

Conditions

Heart Failure

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Heart Failure

NCT06205225

Where you'd take part

This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Rush University Medical Center

    Chicago, Illinoisstudy coordinator listed

    Recruiting

  • University of Illinois Hospital & Health Sciences System

    Chicago, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Spyros Kitsiou, PhD · PRINCIPAL_INVESTIGATOR · University of Illinois at Chicago

Who to contact

Spyros Kitsiou, PhD
[email protected]
312-413-4227
Email the study team

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Eligibility criteria

Inclusion

Diagnosis of Stage C Heart Failure
≥ 18 years of age
Transthoracic Echocardiogram or Cardiac MRI performed in the last 3 years and LVEF results available
Patient is actively treated with oral loop diuretics for chronic heart failure
Hospitalization due to acute decompensated heart failure within 24 months before randomization and/or insufficient self-care per SCHFI assessment (score of ≤3, in at least two items of the SCHFI v7.2 maintenance, symptom monitoring, or self-care management subscale)
Ability to speak and read English

Exclusion

Implanted ventricular assist device
High urgent listed for heart transplantation
Acute coronary syndrome within the last 7 days before randomization
Revascularization and/or CRT implantation within 28 days before randomization
Planned revascularization, transcatheter aortic valve implantation, MitraClip and/or CRT implantation within 3 months after randomization
End-stage HF (hospice candidate)
Discharge to a setting other than home
Individuals who have a home nurse or are not able to take care of self (eat, dress, walk, bathe, take medications, or use the toilet)
Chronic renal insufficiency with hemodialysis or estimated Glomerular Filtration Rate \<25 mL
Active cancer, currently undergoing treatment (e.g. radiation immunotherapy)
Existence of any disease reducing life expectancy to less than 1 year
Cognitive impairment (e.g., Dementia, Parkinson disease, Alzheimer disease, MoCA\<18, impaired self-determination, lacking ability to communicate)
Major physical impairment (e.g., inability to walk, bound on a wheelchair)
Unwillingness to use study equipment
Active substance abuse
Currently pregnant, less than 3-month post-partum or pregnancy anticipated during the study
Participation in other treatment studies or remote patient management programs
Participation in the iCardia4H pilot trial (conducted before this study)

What this trial measures

  • Percentage of days lost due to unplanned cardiovascular hospitalizations or death from any cause6 months

    Hospitalization is defined as hospital admission resulting in an overnight stay where the length of stay is at least 24 hours. Events leading to emergency department visit only with a length of stay under 24 hours will not be classified as hospitalization. For a hospitalization to be considered as unplanned the patient must present new symptoms and/or worsening of existing symptoms with the need for immediate admission in a hospital for intensified care. A hospitalization will be considered "cardiovascular" when it is due to cardiovascular causes which includes but is not limited to: HF deterioration, acute myocardial infarction, arrhythmia, HF, pulmonary embolism, cerebrovascular disease (e.g., stroke), severe bleeding, endocarditis, etc.