Observational Study on Cannabis Use and Immunotherapy in Cancer

This study, called IMPACT-C, is looking at how people with cancer who are receiving immunotherapy (treatments that help your body's immune system fight cancer) manage their symptoms. Researchers want to understand how different methods, including cannabis, affect symptoms like pain, sleep, and anxiety. You might be able to join if you are at least 21 years old, have cancer, are planning to use or are already using immunotherapy, and experience pain. This study will help us learn more about managing cancer symptoms and improving patient care. The study is currently unclear on its recruitment status and aims to enroll 450 participants.

Study design
This is an observational study, meaning researchers will watch and collect information without giving specific treatments. It aims to enroll 450 participants.
What's involved
You would complete online surveys and short daily assessments for 7 days at 0, 1, 2, 4, 6, 9, and 12 months.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for 12 months after starting the study.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06206941

IMmunotherapy: Prospective Assessment of Cannabis Treatment in Cancer

Recruiting
Not specifiedAges 18+Observational
State University of New York at Buffalo
~450 participants
Updated 2026-08-26 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Patient Reported Outcomes Measurement Information System: Pain interference
Measured over 0,1,2,4,6,9 and 12 months
+7 more outcomes measured
Cancer
2 sites across 2 states
Oregon1
Pennsylvania1

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

adult age of 18 years or older
cancer diagnosis and planning or using immunotherapy treatment,
pain and spend less than 50% in bed or chair
fluent in english language

Exclusion

use synthetic cannabis or only use Cannabidiol (CBD)
non users but used in the past 3 months
Patients receiving immunosuppressants or organ transplant recipients.
Patients within 6 months of Hospice care.
Pain that limits movement to more than 50% of their day in bed or chair
  • Patient Reported Outcomes Measurement Information System: Pain interference0,1,2,4,6,9 and 12 months

    Pain interference with daily life and enjoyment on a 5 item scale of not at all to very much. Higher score indicates worse outcome.

  • Patient Reported Outcomes Measurement Information System: Sleep0,1,2,4,6,9 and 12 months

    PROMISE sleep disturbance on a 5 item scale of not at all to very much. Higher score indicates worse outcome.

  • Patient Reported Outcomes Measurement Information System:Anxiety0,1,2,4,6,9 and 12 months

    Anxiety on a 5 item scale of never to always. Higher score indicates worse outcome. Higher score indicates worse outcome.

  • Adverse reaction of Cannabis0,1,2,4,6,9 and 12 months

    Adverse reaction to Cannabis Scale of present side effects and 5 item scale of how distressing the symptoms were experienced. Higher score indicates worse outcome.

  • Cannabis Use Disorder Identification Test0,1,2,4,6,9 and 12 months

    Cannabis Use Disorder Identification Test (CUDIT), the usage of cannabis and 5 item scale of never to daily or almost daily. Higher score indicates worse outcome.

  • Patient Reported Outcomes Measurement Information System: Depression0,1,2,4,6,9 and 12 months

    Emotional Distress-Depression on a 5 item scale of never to always, level of sexual activity, emotional well-being, functional well-being and additional concerns on a 5 item scale not at all to very much. Higher score indicates worse outcome.

  • Patient Reported Outcomes Measurement Information System: Cognitive Function0,1,2,4,6,9 and 12 months

    Cognitive Function-Abilities on a 5 item scal not at all to very much. Higher score indicates better outcome.

  • Patient Reported Outcomes Measurement Information System: Fatigue0,1,2,4,6,9 and 12 months

    Level of fatigue on a 5 item scale of never to always. Higher score indicates worse outcome.