TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

This study, called TEMPUS ARIES, is observing people with cancer to understand how their cancer changes over time. Researchers will collect blood samples to look at circulating tumor DNA (ctDNA), which are tiny pieces of cancer DNA found in the blood. This is not a study testing a new treatment; you will receive your usual cancer care. The study aims to track changes in ctDNA over five years. You can join if you are 18 to 99 years old, have a cancer diagnosis, and are willing to provide blood samples and give your informed consent. About 500 people are expected to participate.

Study design
This is an observational study, meaning it watches participants without giving them a specific intervention. It plans to enroll about 500 participants.
What's involved
You would have additional blood samples collected at specific times, in addition to your standard cancer care.
Compensation
Not stated in the trial record.
Follow-up
Changes in ctDNA will be measured for five years.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06207032

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Recruiting
Not specifiedAges 18–99Observational
Tempus AI
~500 participants
Updated 2026-02-24 on ClinicalTrials.gov

At a glance

Recruiting sites
25 of 32 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Changes in ctDNA from baseline, on-treatment and post-treatment blood samples.
Measured over 5 years
Cancer
32 sites across 19 states
Illinois5
Missouri4
Georgia2
Indiana2
Nevada2
New Jersey2
New York2
Ohio2
  • Michelle Ting-Lin, MD · STUDY_DIRECTOR · Tempus AI, Inc.

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  • Changes in ctDNA from baseline, on-treatment and post-treatment blood samples.5 years

    Assess ctDNA kinetics using ctDNA clearance factors such as time to clearance, best overall clearance rate, best confirmed clearance, and time to ctDNA recurrence and correlate with standard of care therapy real-world outcomes such as overall survival, progression-free survival, time to next treatment, and time to treatment discontinuation.