Intraperitoneal Paclitaxel for Metastatic Appendiceal Adenocarcinoma

This study is testing a treatment called paclitaxel, given directly into the belly (intraperitoneal), for people with appendiceal adenocarcinoma that has spread (metastatic) and cannot be removed by surgery. The main goals are to find the safest dose of paclitaxel and to see how well it shrinks tumors. You might be able to join if you are 18 or older, have metastatic appendiceal adenocarcinoma in your belly, and are not able to have surgery. The study is looking for 39 participants and is currently unclear if it is recruiting.

Study design
This is a Phase I/II interventional study, meaning it will first look for the best dose and then study how well the treatment works. It plans to enroll 39 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your safety and side effects will be monitored throughout the study, which is expected to last an average of 1 year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06207305

A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma

Recruiting
PHASE1Ages 18+InterventionalTreatment
M.D. Anderson Cancer Center
~39 participants
Updated 2026-07-16 on ClinicalTrials.gov
What's tested:DexamethasoneDiphenhydramineFamotidinePaclitaxel

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Safety and adverse events (AEs)
Measured over Through study completion; an average of 1 year.
Metastatic Appendiceal Adenocarcinoma
Intraperitoneal Paclitaxel
1 sites across 1 states
Texas1
  • Beth Helmink, MD · PRINCIPAL_INVESTIGATOR · M.D. Anderson Cancer Center

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  • Safety and adverse events (AEs)Through study completion; an average of 1 year.

    Incidence of Adverse Events, Graded According to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI CTCAE) Version (v) 5.0