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Movement Retraining for Knee Osteoarthritis

This study is looking at how a walking exercise called gait retraining can help people with knee osteoarthritis (a condition where cartilage in the knee wears down). Researchers want to see if you can learn to change how you use your calf muscles while walking, and if this change can reduce the stress on your knee. You might be able to join if you are an adult with knee osteoarthritis for at least six months, can walk without help for an hour, and have typical knee pain between 1 and 4 on a 0-10 scale. The main goal is to measure how much the force on your knee changes after learning this new walking technique.

Study design
This is an interventional study with a planned enrollment of 31 participants.
What's involved
You would learn to change your muscle coordination while walking, receiving feedback after each step during in-lab and out-of-lab sessions.
Compensation
Not stated in the trial record.
Follow-up
Knee contact force will be evaluated during feedback walking in the second in-lab session and out-of-lab session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06208631

Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis

Recruiting
NAAges 18+Interventional
Stanford University
~31 participants
Updated 2026-06-23 on ClinicalTrials.gov
What's tested:Gait retraining

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change from baseline in knee contact force
Measured over Evaluated during the 30 minutes of feedback walking in the second in-lab session and out-of-lab session

Conditions

Osteoarthritis, Knee

Explore related trials

Osteoarthritis of knee

NCT06208631

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Stanford Human Performance Lab

    Stanford, Californiastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

Study leadership

  • Scott L Delp, PhD · PRINCIPAL_INVESTIGATOR · Stanford University

Who to contact

Study Team
[email protected]
650-721-2547
Email the study team

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Eligibility criteria

Inclusion

Medial and/or lateral compartment knee osteoarthritis
Diagnosed with knee osteoarthritis of at least six months duration
Ambulatory without aids
Able to walk for at least 60 minutes
Typical pain rating of 1-4 on scale of 0-10
Able to reduce gastrocnemius muscle activation by 10% from baseline

Exclusion

History of symptomatic arthritis in lower limb joints other than the knees
Replacement of any lower extremity joint
Symptoms originating from the patellofemoral joint
Body mass index equal to or greater than 35
Nerve or muscle disease associated with walking difficulty
History of rheumatoid arthritis, gout, or autoimmune disease
History of lower limb fracture or surgery requiring hospitalization
Pregnant

What this trial measures

  • Change from baseline in knee contact forceEvaluated during the 30 minutes of feedback walking in the second in-lab session and out-of-lab session

    Knee contact force will be evaluated using motion capture data and musculoskeletal modeling and simulations, for participants that are able to reduce gastrocnemius activation.