This study is looking at bone health in adolescents (ages 13-20) with cystic fibrosis (CF). Researchers want to understand if young people with CF have more fat in their bone marrow and how this might affect their bone strength. They will use several imaging tests, including magnetic resonance relaxometry (MRI scans to measure fat in bone marrow), magnetic resonance spectroscopy (another type of MRI to measure fat), DXA (a scan to measure bone density), and pQCT (a scan to measure bone density in the lower leg). Blood tests will also be done to check markers related to bone formation, breakdown, and inflammation. The study aims to see if increased bone marrow fat in CF patients is linked to weaker bones over one year. You may be able to join if you are 13-20 years old, have CF with pancreatic insufficiency, and have been on a stable treatment plan for at least three months.

Study design

This is an observational study planning to enroll 36 adolescents with cystic fibrosis and compare them to healthy individuals. It is not testing a new treatment.

What's involved

Participants will undergo magnetic resonance relaxometry, magnetic resonance spectroscopy, DXA, pQCT scans, and blood draws at the beginning of the study and again after one year.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed for one year, with assessments at baseline and one year.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.