Reducing Chronic Hypertension After Preeclampsia
This study is looking at whether early and intensive blood pressure control after pregnancy can reduce the risk of developing long-term (chronic) high blood pressure and improve heart and blood vessel health. If you recently experienced a hypertensive disorder of pregnancy (like preeclampsia or gestational hypertension) and are within 4 days postpartum, you might be able to join. The study will compare two approaches: one group will receive the medication nifedipine ER (extended-release) if their blood pressure is 140/90 mmHg or higher, and the other group will receive nifedipine ER if their blood pressure is 150/100 mmHg or higher. The main goal is to see if the intensive blood pressure control group has a lower rate of stage I hypertension one year after delivery. The study is currently recruiting participants.
- Study design
- This is a multicenter randomized controlled trial involving 618 participants. Participants will be randomly assigned to either an intensive blood pressure control group or a usual care group.
- What's involved
- You would undergo blood pressure monitoring, cardiovascular function assessments, and biomarker collection at the start, at 6 weeks, and at 12 months postpartum.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for one year postpartum to assess the primary outcome.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Anna Palatnik, MD · PRINCIPAL_INVESTIGATOR · Medical College of Wisconsin
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Chronic hypertensionOne year postpartum
Diagnosis of chronic hypertension, defined as stage I hypertension with BP \>130/80 mmHg