Response to Massage in Neck Pain Study

This study is looking at how different types of massage affect neck pain. Researchers want to see if your pain sensitivity (how much pressure it takes to feel pain) can predict how much relief you get from a "pain inducing massage." They also want to compare the pain relief from a "pain inducing massage" to a "pain free massage" or placing your hand in a cold water bath. You might be able to join if you are between 18 and 60 years old, have been experiencing neck pain for at least three months, and rate your pain as 4 out of 10 or higher in the last 24 hours. The main goal is to measure your pressure pain threshold (how much pressure you can handle before feeling pain) before and right after the intervention.

Study design
This is an interventional study with 53 planned participants. Participants with neck pain will be randomly assigned to one of three groups: a pain inducing massage, a pain free massage, or a cold water bath.
What's involved
You would receive one of three interventions: a pain inducing massage, a pain free massage, or a cold water bath. Each intervention involves four repetitions of 60 seconds each, for a total of 240 seconds. Your pressure pain threshold will be measured before and immediately after the intervention.
Compensation
Not stated in the trial record.
Follow-up
Your pressure pain threshold will be measured immediately following the intervention.

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NCT06224829

Response to Massage in Neck Pain

Recruiting
NAAges 18–60InterventionalTreatment
University of Florida
~53 participants
Updated 2025-07-24 on ClinicalTrials.gov
What's tested:Pain Inducing MassagePain Free MassageCold Water Bath

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Pressure Pain Threshold
Measured over Baseline and immediately following the intervention
Neck Pain
1 sites across 1 states
Florida1

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Eligibility criteria

Inclusion

Age 18 to 60 years old
Currently experiencing neck pain with or without arm pain
Neck pain symptom intensity rated as 4/10 or higher during the last 24 hours
Neck pain for greater than or equal to 3 months

Exclusion

Non- English speaking
Systemic medical conditions known to affect sensation (e.g. diabetes)
History of neck surgery or fracture within the past 6 months
Current history of chronic pain condition other than neck pain
Diagnosis of cervical radiculopathy or cervical myelopathy
History of whiplash
Currently using blood thinning medication
Any blood clotting disorder such as hemophilia
Any contraindication to application of ice, such as: uncontrolled hypertension, cold urticaria, cryoglobulinemia, paroxysmal cold hemoglobinuria, and circulatory compromise
Pregnancy
  • Pressure Pain ThresholdBaseline and immediately following the intervention

    Pressure applied to the web space of the foot with a digital pressure algometer applied at 1 kg/s. Participants will be instructed to indicate when the sensation first changes from pressure to pain (pain threshold)