This study is looking at how open-label placebo pills (empty capsules made of microcrystalline cellulose) might help people with chronic pain, specifically those with temporomandibular disorders (TMD). Researchers want to see if taking these placebo pills, especially with guidance on how placebos work, can reduce chronic pain intensity and improve sleep quality. You might be able to join if you are 18-88 years old, speak English, have had TMD for at least 3 months, and have a smartphone. The study will measure your chronic pain intensity and sleep efficiency daily over 45 days to see if these improve.

Study design

This is a randomized clinical trial with 111 participants. You would be assigned to one of three groups: open-label placebo with expectation management, open-label placebo only, or standard care.

What's involved

You would participate in a 2-day phenotyping phase, including an in-person visit and at-home monitoring, followed by a 45-day intervention phase.

Compensation

Not stated in the trial record.

Follow-up

Your chronic pain intensity and sleep efficiency will be measured daily over the 45-day intervention phase.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.