A Novel Intervention for Weight Loss in Young Adults

This study is looking for young adults (ages 18-40) who are overweight or obese to test a new way to help with weight loss. You would receive diet and exercise goals and coaching. The main goal is to see how this combination of coaching and technology helps people lose weight over 6 months. To join, you need to be generally healthy, have a smartphone, and not have had major weight changes recently. The study is currently looking for 140 participants.

Study design: This is an interventional study, meaning participants will receive a specific treatment. It plans to enroll 140 participants.
What's involved: You would participate for about 6 months, with up to 5 visits to the University of Chicago. These visits include blood draws and surveys, and you'll use a smartphone app, digital scale, and activity monitor daily.
Compensation: Not stated in the trial record.
Follow-up: Weight loss will be measured at the beginning and after 6 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

A Novel Intervention for Weight Loss in Young Adults

Recruiting

NAAges 18–40InterventionalTreatment

University of Chicago

~140 participants

Updated 2025-11-17 on ClinicalTrials.gov

What's tested:LifestyleLifestyle II

At a glance

Recruiting sites

1 of 1 listed site is recruiting right now

RecruitingSuspended, closed, or not yet open

What they're measuring

Weight loss

Measured over Baseline and 6 months

Conditions

Weight Loss

Where it's being run

1 sites across 1 states

Illinois1

Study leadership

Esra Tasali, MD · PRINCIPAL_INVESTIGATOR · University of Chicago

Who to contact

Olivia Hughes

[email protected]

7737022348

Email the study team

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Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

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Eligibility criteria

Inclusion

Overweight or obese (BMI 25.5- 34.9 kg/m2) men and women

Ages 18 to 40 years

Weight stable (no change \>25 lbs in the past 3 months)

Owns a smartphone and willing to install the study app

Exclusion

Presence of obstructive sleep apnea or history of any other sleep disorder.

Irregular menses, menopausal symptoms or post-menopausal, currently pregnant, trying to get pregnant or nursing

Regular travel across time zones

Subjects who are currently following a weight loss regimen or any other special diet or exercise programs

Increased fractional lean body mass (e.g., athletes)

Unable to walk, using an assistive device for mobility, or any contraindications to exercise

Diabetes

Claustrophobia

Excessive alcohol (\>2 drinks/day) or caffeine (\>300mg/day) intake, regular nicotine use, substance abuse.

Abnormal findings on screening blood testing.

Participants taking any prescription, over-the-counter drugs/supplements that can affect sleep or weight.

Major psychiatric or any eating disorder, and any acute or chronic medical condition that increase the risk of interventions (e.g., heart disease)

Any underlying disease likely to limit life span and/or increase risk of interventions including cardiovascular disease (e.g. unstable angina, heart failure requiring hospitalization in the past 6 months, significant heart block or arrhythmias, NYHA Class\>2), pulmonary disease with dependence on oxygen or daily use of bronchodilators, cancer requiring treatment in the past 5 years unless the prognosis is considered good, active or chronic infection, thyroid disease and other endocrine disorders (e.g. Cushing syndrome, acromegaly), hepatitis or other chronic gastrointestinal disease (pancreatitis, inflammatory bowel disease), renal disease, significant anemia, recent surgery or significant abdominal surgery, major psychiatric or any eating disorder, acute coronary syndrome or stroke in the past 6 months

What this trial measures

Weight lossBaseline and 6 months
Change in weight \[kg\] at 6 months. Weight will be measured by research staff during each visit in the morning in duplicate in the fasted state after voiding using calibrated digital scales, wearing a hospital gown.

Trialytics