Famotidine and Antacids for Dyspepsia in the Emergency Department

This study is looking at two common treatments for dyspepsia (upset stomach or indigestion), GERD (acid reflux), and acid reflux in people who come to the emergency department. Researchers want to see if intravenous (IV) famotidine or oral Maalox/Mylanta is better at reducing pain. You might be able to join if you are at least 18 years old, have been diagnosed with dyspepsia, and have upper abdominal pain that is at least a 3 on a pain scale. The study aims to see which treatment reduces pain more effectively within one hour. The current recruitment status is unclear.

Study design
This is an interventional study planning to enroll about 80 participants. You would be randomly assigned to receive either intravenous famotidine or oral Maalox/Mylanta.
What's involved
You would receive one of the study medications and have your pain measured at several time points over 60 minutes.
Compensation
Not stated in the trial record.
Follow-up
Your pain will be measured for 60 minutes after receiving the study medication.

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NCT06241183

Famotidine and Antacids for Treatment of Dyspepsia

Recruiting
PHASE4Ages 18+InterventionalTreatment
Stony Brook University
~80 participants
Updated 2026-06-02 on ClinicalTrials.gov
What's tested:Intravenous FamotidineOral Maalox/ Mylanta

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Verbal Numerical Pain Score
Measured over at 1 hour
Dyspepsia
GERD
Acid Reflux
1 sites across 1 states
New York1

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  • Verbal Numerical Pain Scoreat 1 hour

    Patients will be asked to rate their pain on a scale of 0 to 10 with 0 indicating no pain and 10 indicating the worst pain imaginable every 15 minutes for 60 minutes.