Breaking Sitting with Exercise for Brain Health

This study is looking at whether short exercise breaks during sitting can improve brain health in adults aged 40-75. Researchers will compare two types of exercise breaks: High-Intensity Interval Training (HIIT) and Light-Intensity Interval Training (LIIT). You would participate if you are generally healthy, sedentary (sit for 6+ hours daily), and not very physically active. The main goal is to see if these exercise breaks improve brain activity and cognitive functions (like thinking and memory). The study aims to enroll 54 participants, but its current status is unclear.

Study design
This is a randomized crossover study involving 54 older adults. You would experience both the HIIT and LIIT break conditions in a balanced order.
What's involved
You would participate in two 3.5-hour sessions, each involving interruptions to sitting with 6-minute exercise breaks every 30 minutes. There will be a 1 to 4-week break between sessions.
Compensation
Not stated in the trial record.
Follow-up
Brain activity and cognitive functions will be measured immediately before, during, and immediately after each 3.5-hour intervention session.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06243016

Breaking Sitting with High-intensity Interval Training for Brain Health

Recruiting
NAAges 40–75InterventionalPrevention
University of Illinois at Urbana-Champaign
~54 participants
Updated 2025-02-07 on ClinicalTrials.gov
What's tested:High-Intensity Interval Training (HIIT) Breaks to SittingLight-Intensity Interval Training (LIIT) Breaks to Sitting

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Change in task-evoked brain activity
Measured over Immediately before intervention, 2 x during the intervention (50 min and 120 min into the intervention), and immediately after the intervention
Aging

NCT06243016

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • University of Illinois at Urbana-Champaign

    Urbana, Illinoisstudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Dominika M Pindus, Ph.D. · PRINCIPAL_INVESTIGATOR · University of Illinois Urbana-Champaign

Opens a ready-to-send draft in your own email app — review before sending.

  • Change in task-evoked brain activityImmediately before intervention, 2 x during the intervention (50 min and 120 min into the intervention), and immediately after the intervention

    EEG will be used to measure event-related brain potentials including the P3b-component during an inhibitory control task.