This observational study, called ARISE, is looking at how aspirin affects pregnant individuals at risk for preeclampsia (a serious blood pressure condition during pregnancy). Researchers want to understand if aspirin changes certain tiny particles called Extracellular Vesicles (EVs) in your blood, which come from both you and the baby. By studying these EVs, they hope to find new ways to monitor how well the placenta is working and how it responds to aspirin treatment. The study will enroll about 1000 pregnant individuals who are already taking aspirin as part of their care or a separate study. They will collect samples from enrollment until delivery, up to 29 weeks of pregnancy, to see if the EV profiles differ between those who do or don't develop preeclampsia.

Study design

This is an observational study, meaning researchers will watch and collect information without providing any specific intervention. It aims to enroll about 1000 participants.

What's involved

Not specified in the trial record.

Compensation

Not stated in the trial record.

Follow-up

Participants will be followed from enrollment until delivery, up to 29 weeks.

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