LIVER-R: Real-World Study of Durvalumab-Based Treatments for Hepatobiliary Cancers
This study, called LIVER-R, is observing how durvalumab-based treatments work for people with hepatobiliary cancers (cancers of the liver, gallbladder, or bile ducts) in real-world settings. Researchers are collecting information on patients who are already receiving durvalumab-based regimens, such as STRIDE or durvalumab combined with chemotherapy (like GemCis). The study aims to understand how long patients live after starting these treatments. You may be able to join if you are an adult (18 years or older) with a confirmed hepatobiliary cancer that your doctor has decided to treat with a durvalumab-based regimen. The study is currently unclear on its recruitment status.
- Study design
- This is an observational study, meaning researchers will collect information from your routine medical care. It aims to include about 4490 participants across many countries.
- What's involved
- Data will be collected during your routine doctor visits and from your medical records. This will happen at enrollment and at 6-month intervals.
- Compensation
- Not stated in the trial record.
- Follow-up
- You will be followed for up to 2 years if you have advanced biliary tract cancer, or up to 3 years if you have unresectable hepatocellular carcinoma.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Observational Study Protocol: LIVER-R
At a glance
Conditions
NCT06252753
Where you'd take part
This study runs at 160 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Research Site
Birmingham, Alabamano site contact published
Recruiting
Research Site
Mobile, Alabamano site contact published
Recruiting
Research Site
Phoenix, Arizonano site contact published
Recruiting
Research Site
Coronado, Californiano site contact published
Recruiting
Research Site
Los Angeles, Californiano site contact published
Recruiting
Research Site
Walnut Creek, Californiano site contact published
Recruiting
Research Site
Clermont, Floridano site contact published
Recruiting
Research Site
Gainesville, Floridano site contact published
Recruiting
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
What this trial measures
- Real-world overall survival (rwOS) in all participantsrwOS will be assessed as OS rates at 6, 12, 18, 24, and 36 months, as applicable per the type of hepatobiliary cancer; median OS for a minimum follow-up of 2 years.
rwOS will be calculated as the time from the index date to date of death, by any cause.