Deep Brain Stimulation for Psychosis
This study is exploring the use of Deep Brain Stimulation (DBS) with the Abbott Laboratories Infinity™ implantable system for individuals aged 22 to 70 who have treatment-resistant schizophrenia. DBS involves delivering a small electrical current to a specific area of the brain. The researchers want to see if this device is safe over three years and if it can help change brain activity to a non-psychotic state. They also aim to understand if specific stimulation settings can lead to these changes. This study is currently recruiting a small group of 10 participants.
- Study design
- This is an interventional study with a planned enrollment of 10 participants. The phase of the study is not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for device safety for at least 3 years.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Deep Brain Stimulation for Psychosis
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Bradley Lega, M.D. · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center
- David McDonagh, M.D. · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center
- Nader Pouratian, M.D. · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center
- Carol Tamminga, M.D. · PRINCIPAL_INVESTIGATOR · University of Texas Southwestern Medical Center
Who to contact
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What this trial measures
- Demonstrate device safety3 years
The primary objective is to demonstrate safety of acute and chronic network guided stimulation for treatment-refractory schizophrenia. This is determined if participants with the Deep Brain Stimulation Device demonstrate no significant device related serious adverse events (SAE). Device safety will be measured by number of reported SAE's in year 2 and 3.