Targeted Navigation for Liver Cancer Patients

This study is testing a "Target Navigation Pilot Program" to better understand and address the needs of patients with liver cancer, including hepatocellular carcinoma (HCC), cholangiocarcinoma, and other hepatobiliary cancers. The program involves meeting with a navigator who can speak English, Spanish, or Creole, either in person or virtually. These meetings will happen every two weeks until your first treatment, and then every three months afterward, each lasting about an hour. Researchers want to see how long it takes to first contact you, how long until your first treatment, and the total time spent with the navigator. You may be able to join if you are 18 or older and have been diagnosed with hepatocellular carcinoma. The study aims to enroll 210 participants and is currently recruiting.

Study design
This is an interventional study aiming to enroll 210 participants. It is not specified if it is randomized or blinded.
What's involved
You would meet with a navigator every two weeks until your first treatment, and then every three months after. Each session will last approximately one hour.
Compensation
Not stated in the trial record.
Follow-up
You will be followed for up to 12 months to measure the number of hours for each contact, days to first contact, and days to first treatment.

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NCT06260943

Targeted Navigation in Hepatocellular Carcinoma (HCC)

Recruiting
NAAges 18+InterventionalSupportive care
University of Miami
~210 participants
Updated 2026-07-02 on ClinicalTrials.gov
What's tested:Target Navigation Pilot Program

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Number of Hours for Each Contact
Measured over Up to 12 months
+6 more outcomes measured
Hepatocellular Carcinoma
Cholangiocarcinoma
Hepatobiliary Cancer
1 sites across 1 states
Florida1
  • Patricia Jones, MD · PRINCIPAL_INVESTIGATOR · University of Miami

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Eligibility criteria

Inclusion

HCC Patients:
Enrolled or eligible for enrollment in Unified Prospective Registry and Biorepository of Patients with Chronic Liver Disease or Hepatobiliary Cancers Including Hepatocellular Carcinoma (HCC) and Cholangiocarcinoma.
Diagnosis of hepatocellular carcinoma, confirmed by clinical chart review and International Classification of Diseases, Tenth Revision (ICD-10) C22.0.
Adults, age 18 or older
Able to provide informed consent
All other interviewees:
Advocates who will self-identify as having had HCC.
Others who self-identify as either a caregiver or support person of an HCC patient.

Exclusion

Unable to speak Spanish or English
West Haven Grade 2 or higher hepatic encephalopathy19 or other cognitive impairment.
Adults unable or unwilling to consent
Individuals who are not yet adults (infants, children, teenagers)
Prisoners
Given that this study is minimal risk and there are no risks to a potential fetus, investigators will not exclude pregnant women; however, no data about pregnancy or their fetus is being collected
  • Number of Hours for Each ContactUp to 12 months

    The length of time of each contact will be assessed in number of hours. Contact is defined as the length of time the navigator meets with the participant.

  • Number of Days to First ContactUp to 12 months

    The time to first contact since hepatocellular carcinoma diagnosis will be assessed in number of days.

  • Number of Days to First TreatmentUp to 12 months

    The time to first treatment will be assessed in number of days.

  • Number of Months of Total NavigationUp to 12 months

    The length of total navigation will be assessed in number of months.

  • Number of Participants that Die Within One YearUp to 1 year

    Number of participants that die within one year of enrollment in the navigation program.

  • Proportion of Participants Enrolled in Clinical ResearchUp to 12 months

    The proportion of participants enrolled in clinical research will be reported.

  • AcceptabilityEnrollment

    Percentage of approached individuals who agree to participate