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Observational Study on Sex Differences in Neurocirculatory Control in Obstructive Sleep Apnea

This observational study aims to understand if there are differences between men and women in how their nervous system controls blood pressure when they have untreated obstructive sleep apnea (OSA). Researchers will look at your blood pressure, arterial stiffness (how flexible your arteries are), and endothelial function (how well the inner lining of your blood vessels works) at the beginning of the study. The study is looking for 60 participants between 20 and 70 years old. You cannot join if you have certain health conditions like heart disease, diabetes, or if you are pregnant. The current recruitment status is unclear.

Study design
This is an observational study designed to enroll 60 participants. It is not specified if it is randomized or blinded.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Not specified.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06261034

A Study of Sex Differences in Neurocirculatory Control

Recruiting
Not specifiedAges 20–70Observational
Mayo Clinic
~60 participants
Updated 2026-01-07 on ClinicalTrials.gov

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Blood pressure
Measured over Baseline
+2 more outcomes measured

Conditions

Obstructive Sleep Apnea

Explore related trials

Obstructive Sleep Apnea

Where it's being run

1 sites across 1 states
Minnesota1

Study leadership

  • Joshua Bock, PhD · PRINCIPAL_INVESTIGATOR · Mayo Clinic

Who to contact

Joshua Bock, PhD
[email protected]
(507) 422-0768
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

20-70 years of age

Exclusion

Coronary artery disease
Heart failure
Pregnancy
COPD
Diabetes
CKD
Sleep disorders other than OSA
Shift workers
Individuals who typically go to sleep after midnight
Individuals who traveled across ≥2 time zones within one week of study visits
BMI ≥40.0kg/m2
Use of nicotine-containing products within the two years preceding study visits
Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures

What this trial measures

  • Blood pressureBaseline

    Measured in millimeters of mercury (mmHg).

  • Arterial stiffnessBaseline

    Measured by applanation tonometry reported as aortic pulse wave velocity (m/sec)

  • Endothelial functionBaseline

    Ultrasound assessment of flow-mediated vasodilation of the brachial artery. Brachial artery diameter and blood velocity will be measured after deflation to measure endothelial function.