Plasma Rich in Growth Factors in Corneal Endothelial Transplantation
{ "Plasma Rich in Growth Factors for Corneal Endothelial Transplantation", "This study is looking at whether briefly treating donor corneal tissue with Plasma Rich in Growth Factors (PRGF) before a corneal transplant (endothelial keratoplasty) can help reduce the loss of cells after surgery. PRGF is a mixture of proteins and growth factors taken from your own blood. The study aims to see if this treatment is safe and effective for people with Fuchs' Endothelial Dystrophy or Corneal Edema. You may be able to join if you are between 18 and 80 years old and are having an endothelial keratoplasty at Bascom Palmer Eye Institute or Price Vision Group. The study plans to enroll 100 participants. The main goal is to measure the change in endothelial cell percentage at 6 months after surgery.", "design": "This is an interventional study planning to enroll 100 participants. The study is investigating a procedure where donor tissue is briefly treated with PRGF.", "commitments": "If you participate, your donor corneal tissue will be incubated with PRGF for 15 minutes in the operating room before your endothelial keratoplasty. Your endothelial cell percentage will be measured at the start of the study and again at 6 months.", "compensation": "Not stated in the trial record.", "follow_up": "Participants will be followed for at least 6 months after treatment to measure changes in endothelial cell percentage.", }
- Study design
- Not specified.
- What's involved
- Not specified in the trial record.
- Compensation
- Not stated in the trial record.
- Follow-up
- Not specified.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Plasma Rich in Growth Factors in Corneal Endothelial Transplantation
At a glance
Conditions
Where it's being run
2 sites across 2 statesStudy leadership
- Alfonso L Sabater, MD · PRINCIPAL_INVESTIGATOR · Bascom Palmer Eye Institute
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Do you actually qualify for this trial?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Change in endothelial cell percentageBaseline, 6 months
Central corneal endothelial cell percentage will be assessed by specular microscopy and compared with the baseline donor endothelial cell percentage measured by the provider eye bank to determine endothelial cell changes.