Oxytocin Rest for Prolonged Labor Study

This study is looking at a new way to help with prolonged labor (when labor takes a long time) or when labor induction isn't working. It's testing whether a 60-minute "oxytocin rest" can reduce the chance of needing a C-section. Oxytocin is a medicine often used to help contractions. An "oxytocin rest" means stopping the oxytocin for a short time and then restarting it, hoping to make contractions stronger. This study is for women aged 18 to 55 who are at least 36 weeks pregnant with a single baby and are experiencing prolonged labor while already receiving oxytocin. The main goal is to see if this rest period lowers the C-section rate. The study is currently recruiting 350 participants, but its overall status is unclear.

Study design
This is an open-label randomized study, meaning you and your healthcare team will know which treatment you receive. About 350 participants will be randomly assigned to either the oxytocin rest group or the usual care group.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome, C-section rate, is measured at the time of delivery. Other outcomes related to labor length and maternal/neonatal health will also be assessed.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06268431

Oxytocin Rest to Reduce Cesarean Delivery

Recruiting
NAAges 18–55InterventionalTreatment
Christiana Care Health Services
~350 participants
Updated 2024-10-17 on ClinicalTrials.gov
What's tested:Oxytocin rest

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Cesarean rate
Measured over At time of delivery
Prolonged Labor
Failed Induction
Labor Dystocia
1 sites across 1 states
Delaware1
  • Teresa C Logue · PRINCIPAL_INVESTIGATOR · Christiana Care Health Services
  • Matthew K Hoffman · PRINCIPAL_INVESTIGATOR · Christiana Care Health Services

Opens a ready-to-send draft in your own email app — review before sending.

Do you actually qualify for this trial?

Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.

Check eligibility for this trial ~2 min · HIPAA-protected · delete anytime
Eligibility criteria

Inclusion

≥18 years of age
Singleton gestation in vertex presentation
≥36 weeks gestation
Prolonged latent labor, defined as cervical dilation \<6cm after ≥8 hours since rupture of membranes and on continuous oxytocin

Exclusion

Not meeting the above criteria
Any contraindication to continuous oxytocin at time of randomization
Cesarean section anticipated by the clinical team at time of randomization (for any reason excepting labor dystocia)
\>18 hours between rupture of membranes and randomization
Known intraamniotic infection at randomization
Fetal demise
Any contraindication to vaginal delivery
Maternal eclampsia
  • Cesarean rateAt time of delivery

    Number of participants delivered by cesarean