This study is looking at whether a technology called transcranial focused ultrasound (tFUS) can help people with anxiety disorders. tFUS uses sound waves to temporarily change brain activity without surgery. We want to see if tFUS can help reduce behaviors like escape or avoidance that are common in anxiety. You might be able to join if you are 18-65 years old, have an anxiety disorder (like Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Specific Phobia, PTSD, OCD, or adjustment disorder with anxiety), and are currently seeking mental health treatment. The study will measure changes in your Fear-Potentiated Startle Reflex (a way to measure fear responses) right before and after the tFUS treatment. This study is currently recruiting 40 participants.

Study design

This is an interventional study with 40 planned participants. It compares active transcranial focused ultrasound (tFUS) to a sham (inactive) tFUS device.

What's involved

You would have 3 visits at the Medical University of South Carolina. These visits include interviews, surveys, and tasks where your brain activity is measured using MRI.

Compensation

Not stated in the trial record.

Follow-up

Your Fear-Potentiated Startle Reflex will be measured immediately before and immediately after stimulation (approximately 10 minutes between assessments).

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.