NCT06275191
Alternatives to Dental Opioid Prescribing After Tooth Extraction
Enrolling by Invitation
NAAges 12–25InterventionalDouglas OylerInvestigator-initiated
~38,159 participants
Updated 2026-06-10 on ClinicalTrials.gov
What's tested:Multicomponent interventionUsual care
At a glance
Recruiting sites
0 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Odds of post-extraction opioid prescription to adolescent/young adults after tooth extraction
Measured over Same calendar date as dental extraction. Electronic health records will be extracted for the duration of the 4-year study period.
Conditions
Where it's being run
1 sites across 1 statesKentucky1
Study leadership
- Douglas R Oyler, PharmD · PRINCIPAL_INVESTIGATOR · University of Kentucky
- Marcia V Rojas Ramirez, DDS · PRINCIPAL_INVESTIGATOR · University of Kentucky
Who to contact
This trial hasn't published a contact. View it on ClinicalTrials.gov
Do you actually qualify for this trial?
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Eligibility criteria
Inclusion
Actively U.S. licensed dentist or oral surgeon practicing at a participating cluster. Participating clinics were finalized prior to the beginning of the study based on the following criteria: (1) perform tooth extractions on at least 70 AYA patients during a 5-month screening period from July 1, 2022 through November 30, 2022 and (2) electronically prescribe opioids to at least 30% of AYA patients who underwent extraction during the screening period. Additionally, each participating cluster signed a data use agreement (DUA) for sharing electronic health record data, can provide the necessary electronic health record data, and agreed to comply with study procedures and be available for the duration of the study.
Provide a signed and dated informed consent form.
Willing to comply with all study procedures and be available for the duration of the study.
Undergoes any tooth extraction at a participating cluster during the study (intervention condition, transition period, or control condition) between 6-10 days earlier.
Age 12-25 at the time of tooth extraction.
Reads and acknowledges survey cover letter in lieu of a full consent/assent process.
Can access the electronic survey using an internet-capable device.
What this trial measures
- Odds of post-extraction opioid prescription to adolescent/young adults after tooth extractionSame calendar date as dental extraction. Electronic health records will be extracted for the duration of the 4-year study period.
The primary outcome is a patient-level binary indicator for being prescribed an opioid. The value for this outcome variable is equal to 1 if the patient is prescribed an opioid, whereas this variable takes on a value of 0 if this patient is not prescribed an opioid. Opioid prescription will be defined as an electronic order (from the electronic health record) for an opioid analgesic (e.g., hydrocodone, oxycodone, tramadol, morphine, fentanyl, etc.) on the same calendar date as the tooth extraction appointment.