Observational Study on Toxins and Gastrointestinal Health
This observational study aims to understand how different toxins, such as environmental toxins, heavy metals, PFAS (per- and polyfluoroalkyl substances), and mycotoxins, might affect your gastrointestinal (GI) and overall health. Researchers will analyze urine samples to measure these toxins and then compare those levels to your GI symptoms and medical diagnoses. The goal is to see if there's a connection between the amount of toxins in your body and your health. You may be able to join if you are 18 or older, have GI or other symptoms, and are willing to provide urine samples and consent. The study is looking to enroll 250 participants and is currently recruiting.
- Study design
- This is an observational study planning to enroll 250 participants. It will look at the correlation between toxin levels and health scores.
- What's involved
- You would need to provide urine samples and complete a 'Symptom History' form. This would occur over a 1-year period.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be assessed at 1 year for toxin levels, symptoms, and diagnoses.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Correlation of Toxins With Gastrointestinal (GI) and Overall Health
At a glance
Conditions
NCT06278311
Where you'd take part
This study runs at 2 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.
Los Angeles Integrative Gastroenterology and Nutrition, Inc
Los Angeles, Californiastudy coordinator listed
Vibrant America Clinical Lab
Santa Clara, Californiastudy coordinator listed
Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.
Study leadership
- Dr. Farshid S Rahbar, MD · PRINCIPAL_INVESTIGATOR · Los Angeles Integrative Gastroenterology and Nutrition, Inc
- Hari K Krishnamurthy, MS · PRINCIPAL_INVESTIGATOR · Vibrant America Clinical Lab
Who to contact
Opens a ready-to-send draft in your own email app — review before sending.
Want this trial checked against your situation?
Add a private profile and we'll compare every criterion below against your situation — and tell you which ones are met, uncertain, or excluding.
Inclusion
Exclusion
What this trial measures
- Determination of the Total Toxicity score1 year
Mass spectroscopy-based techniques will be used to test participants' urine samples for environmental toxins, heavy metals, PFAS, and mycotoxins. A 'total toxicity score' will be calculated based on the results obtained from the urine analysis of these toxins. The range for total toxicity score lies between 0 (none) to 232 (severe). Higher scores correspond with worse outcomes.
- Determination of the Symptom score1 year
The Symptom History Form is a 90-item questionnaire that will assess participants' digestive and non-digestive symptoms. The scale ranges from 0 (absent) to 1 (present). This form will help determine the 'symptom score.'
- Determination of the Diagnosis score1 year
A diagnosis will be selected by the clinician as part of the medical evaluation during the follow-up patient visit. Diagnosis may be "confirmed," "suspected," or "rule out" all as part of a practitioner's clinical impressions. Each diagnosis score will be presented in the form of an International Classification of Diseases (ICD)-10 code. This will help determine the 'diagnosis score,' which applies only to the patient group.