TAP Trial: Aspirin After Preeclampsia
This study, called the TAP Trial, is looking at whether low-dose aspirin (81 mg) can help women recover after experiencing preeclampsia (a serious high blood pressure condition during pregnancy). You would receive either low-dose aspirin or a placebo (an inactive pill that looks the same) daily for six months after delivery. The main goal of this pilot study is to see if it's practical to conduct a larger trial like this and to assess if aspirin helps improve blood vessel function and lower blood pressure. To join, you must be a woman between 18 and 55 years old who has recently had preeclampsia. You cannot participate if you have certain conditions like pre-pregnancy high blood pressure or diabetes, or an allergy to aspirin. The study is currently unclear about its recruitment status and plans to enroll 60 participants.
- Study design
- This is a pilot, randomized, double-blind study where 60 participants will be assigned by chance to receive either low-dose aspirin or a placebo. Neither you nor your doctor will know which you are receiving.
- What's involved
- You would take a pill daily for six months and monitor your blood pressure at home. You would also have three study visits involving blood pressure measurements, blood draws, questionnaires, and a test called microiontophoresis.
- Compensation
- Not stated in the trial record.
- Follow-up
- Participants will be followed for approximately 6 months postpartum.
AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.
Treatment With Aspirin After Preeclampsia: TAP Trial
At a glance
Conditions
Where it's being run
1 sites across 1 statesStudy leadership
- Alisse K Hauspurg, MD · PRINCIPAL_INVESTIGATOR · UPMC Magee Women's Hospital
Who to contact
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Do you actually qualify for this trial?
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Inclusion
Exclusion
What this trial measures
- Percent of participants eligible, enrolled and retained (feasibility)Baseline to approximately 6 months postpartum
To determine the feasibility of conducting a single-site randomized controlled trial of 6 months of postpartum low-dose aspirin vs. placebo in women with preeclampsia.