Pupil-Indexed Noninvasive Neuromodulation for Paresis

This study is investigating a new way to potentially help people with paresis (muscle weakness or partial paralysis), especially after a stroke. It's testing Transcutaneous Electrical Stimulation, where mild electrical pulses are applied to the skin on your ear. This is compared to a "Sham" treatment, where electrodes are placed but no electricity is given. Researchers believe this stimulation might activate brain pathways that help with learning and recovery. They will measure changes in your ability to control force before, one week after, and one month after the treatment to see if it helps. The study is looking for 110 participants, aged 18 to 75, who have experienced a stroke at least six months ago resulting in hand impairment. The current status of the study is unclear.

Study design
This interventional study plans to enroll 110 participants. It compares Transcutaneous Electrical Stimulation to a Sham treatment.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Your force control will be measured at pre-treatment, one week after treatment, and one month after treatment.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06282406

Pupil-Indexed Noninvasive Neuromodulation

Recruiting
NAAges 18–75InterventionalTreatment
VA Office of Research and Development
~110 participants
Updated 2026-04-24 on ClinicalTrials.gov
What's tested:Transcutaneous Electrical StimulationSham

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Force Control Change
Measured over Pre, 1-week Post, 1-month Post
Paresis

NCT06282406

Where you'd take part

This study runs at 1 site. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

    Pittsburgh, Pennsylvaniastudy coordinator listed

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Michael A. Urbin, PhD · PRINCIPAL_INVESTIGATOR · VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA

Opens a ready-to-send draft in your own email app — review before sending.

  • Force Control ChangePre, 1-week Post, 1-month Post

    Subjects will be tested on the same task used for training that involves controlling finger forces.