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Prolonged Exposure for Suicidal Individuals with PTSD

This study is looking for people aged 18 and older with Post-Traumatic Stress Disorder (PTSD) and suicidal thoughts or behaviors. It aims to see if a type of therapy called Prolonged Exposure (PE), combined with a Crisis Response Plan (CRP), is more effective at reducing suicidal thoughts and attempts than PE with a standard self-guided treatment plan. PE therapy involves recounting traumatic memories and facing trauma-related situations. Researchers will measure changes in suicidal thoughts and behaviors, as well as PTSD symptoms, over three weeks and up to one year after treatment. You must be able to speak and understand English and not have an immediate risk of suicide requiring hospital care.

Study design
This interventional study plans to enroll 100 participants. It compares two different approaches to therapy.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
Participants will be followed for up to one year after treatment to assess outcomes.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06285708

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD

Recruiting
NAAges 18+InterventionalTreatment
Ohio State University
~100 participants
Updated 2026-06-29 on ClinicalTrials.gov
What's tested:Prolonged exposure

At a glance

Recruiting sites
1 of 1 listed site is recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Beck Scale for Suicidal Ideation (SSI)
Measured over During the first 3 weeks and through one year follow up
+2 more outcomes measured

Conditions

PTSD
Suicidal Ideation
Suicide, Attempted
Trauma, Psychological

Explore related trials

Post-Traumatic Stress DisorderSuicidal Ideation

Where it's being run

1 sites across 1 states
Ohio1

Study leadership

  • Jaryd Hiser, Ph.D. · PRINCIPAL_INVESTIGATOR · Assistant Professor

Who to contact

Jaryd Hiser, Ph.D.
[email protected]
614-814-0163
Email the study team

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Do you actually qualify for this trial?

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Eligibility criteria

Inclusion

Current diagnosis of PTSD or subthreshold PTSD; ability to speak and understand the English language; and ability to complete the informed consent process.

Exclusion

Substance use disorder requiring medical management; imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment; and impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania).

What this trial measures

  • Beck Scale for Suicidal Ideation (SSI)During the first 3 weeks and through one year follow up

    19 item self-report assessment of suicidal ideation, range of scores is 0-57, higher score indicates higher suicidal ideation

  • Self-Injurious Thoughts and Behaviors Interview-Revised (SITBI-R)During the first 3 weeks and through one year follow up

    31 item self-report measure of suicidal thoughts and behavior

  • PTSD Checklist for Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 (PCL-5)During the first 3 weeks and through one year follow up

    20 item self-report measure that assesses the 20 DSM-5 symptoms of PTSD. range is 0-80, higher score indicates higher PTSD symptoms