IBS Skin Patch Test Food Allergy Study

This study is looking for people with Irritable Bowel Syndrome (IBS) to see if avoiding certain foods, identified by a skin patch test, can help reduce IBS symptoms. You would be skin patch tested for 80 different foods and food additives to see if you have an allergy. Based on these results, you would either follow a "True avoidance diet" (avoiding foods you're allergic to) or a "Sham avoidance diet" (avoiding randomly selected foods you're not allergic to) for 16 weeks. The main goal is to see how your IBS symptoms change after this diet. You can join if you are 18 or older, have IBS diagnosed by a doctor, or meet specific IBS criteria. The study is currently unclear on its recruitment status and plans to enroll 250 participants.

Study design
This is an interventional study involving 250 participants with Irritable Bowel Syndrome. Participants will be assigned to one of two diet groups for 16 weeks.
What's involved
You would have three office visits within 4-5 days for the skin patch testing. After this, you would follow a specific diet for 16 weeks.
Compensation
Not stated in the trial record.
Follow-up
Your IBS symptoms will be assessed promptly after completing the 16-week avoidance diet.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06288672

IBS Skin Patch Test Food Allergy Study

Recruiting
NAAges 18+InterventionalTreatment
IBS-80, LLC
~250 participants
Updated 2025-12-17 on ClinicalTrials.gov
What's tested:True avoidance dietSham avoidance diet

At a glance

Recruiting sites
2 of 2 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
Post-Avoidance Diet Relative IBS Symptom Global Assessment
Measured over Questionnaire to be completed promptly after completion of 16 week avoidance diet.
Irritable Bowel Syndrome
2 sites across 2 states
Pennsylvania1
West Virginia1
  • Michael B Stierstorfer, MD · PRINCIPAL_INVESTIGATOR · North Wales Dermatology, PLLC

Opens a ready-to-send draft in your own email app — review before sending.

  • Post-Avoidance Diet Relative IBS Symptom Global AssessmentQuestionnaire to be completed promptly after completion of 16 week avoidance diet.

    Participant global assessment of IBS symptoms compared to the three months prior to entering study, assessed by a post-avoidance diet questionnaire. The assessment is a 7 point Likert scale with 1=substantially improved; 2=moderately improved; 3=slightly improved; 4=no change; 5=slightly worse; 6=moderately worse; 7=substantially worse