ADiPOSE Study: Autonomic Dysfunction After Bariatric Surgery

This study, called ADiPOSE, is looking at autonomic dysfunction (AD) and orthostatic intolerance (OI) in people who have had bariatric surgery (weight-loss surgery). AD is a problem with the body's automatic functions, like heart rate and blood pressure, and OI is a type of AD that causes dizziness and lightheadedness when standing up. Researchers want to understand how common these conditions are after bariatric surgery and why they happen. You might be able to join if you are between 18 and 85 years old, have had bariatric surgery (gastric bypass, sleeve gastrectomy, or biliopancreatic diversion with duodenal switch) within the last three years, or are planning to have it soon. The study aims to see how many people develop AD after surgery, measured at 3 months.

Study design
This is an observational study with two phases, looking back at past cases and following new ones. It plans to include 400 participants.
What's involved
Not specified in the trial record.
Compensation
Not stated in the trial record.
Follow-up
The primary outcome of autonomic dysfunction will be assessed at 3 months.

AI-generated from the public study record. Only the study team can confirm whether you're eligible — confirm details with them before making decisions.

NCT06289413

Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

Recruiting
Not specifiedAges 18–85Observational
Kansas City Heart Rhythm Research Foundation
~400 participants
Updated 2025-08-28 on ClinicalTrials.gov
What's tested:Development of AD/OI after BS

At a glance

Recruiting sites
8 of 8 listed sites are recruiting right now
RecruitingSuspended, closed, or not yet open
What they're measuring
To assess the prevalence of and characterize outcome of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS)
Measured over 3 Months
Autonomic Dysfunction
Orthostatic Intolerance

NCT06289413

Where you'd take part

This study runs at 8 sites. They're the same protocol — you choose where, and that choice sets who your contact draft is addressed to.

  • Kansas City Heart Rhythm Institute - Roe Clinic

    Overland Park, Kansasstudy coordinator listed

    Recruiting

  • Overland Park Regional Medical Center

    Overland Park, Kansasstudy coordinator listed

    Recruiting

  • Research Medical Center

    Kansas City, Missouristudy coordinator listed

    Recruiting

  • Research Medical Center Clinic

    Kansas City, Missouristudy coordinator listed

    Recruiting

  • Bariatric and Metabolic Specialists

    Overland Park, Kansasno site contact published

    Recruiting

  • Centerpoint Medical Center

    Independence, Missourino site contact published

    Recruiting

  • Centerpoint Medical Center Clinic

    Independence, Missourino site contact published

    Recruiting

  • Menorah Medical Center

    Overland Park, Kansasno site contact published

    Recruiting

Sites open and close at different times, so the status above is per site — it can differ from the study's overall status.

  • Dhanunjaya Lakkireddy · PRINCIPAL_INVESTIGATOR · Kansas City Heart Rhythm Institute

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Eligibility criteria

Inclusion

Between the age of 18 - 85 years
Can provide consent
Negative urine B-hCG
Continued follow-up with the bariatric surgery team.
BS includes one of the following: gastric bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch.
Phase I: Underwent BS within the last 3 years
Phase II: Will undergo BS within the next 3 months or underwent BS in the last 30 days

Exclusion

Unable to provide consent
Pregnant or breastfeeding
BMI \< 35
Revision surgery of one of the following BS from above
Prior history of autonomic dysfunction prior to BS
Developed AD 72 months post-procedure
No evidence of AD/OI
  • To assess the prevalence of and characterize outcome of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS)3 Months